Cervical cancer is usually entirely curable when detected early through normal Pap screenings. Harper in an interview with CBS News last year.
In males, Gardasil may reduce their risk of genital warts and precancerous lesions caused by HPV.
This reduction in precancerous lesions might be predicted to reduce the rates of penile and anal cancer in men. Gardasil has been shown to also be effective in preventing genital warts in males.
Unlike the Gardasil-based vaccines, Cervarix does not protect against genital warts. Vaccination before adolescence, therefore, makes it more likely that the recipient has not been exposed to HPV.
Since penile and anal cancers are much less common than cervical cancer, HPV vaccination of young men is likely to be much less cost-effective than for young women. The panel's recommendation is intended to prevent genital warts and anal cancers in males, and possibly prevent head and neck cancer though the vaccine's effectiveness against head and neck cancers has not yet been proven.
New evidence suggests that all HPV vaccines are effective in preventing cervical cancer for women up to 45 years of age. In an investigational study, Gardasil reduced the incidence of HPV types 6, 11, 16 and related persistent infection and disease in women through age The study evaluated women who had not contracted at least one of the HPV types targeted by the vaccine by the end of the three-dose vaccination series.
Merck planned to submit this data before the end of to the FDA, and to seek an indication for Gardasil for women through age A recent analysis of data from a clinical trial of Cervarix found that this vaccine is just as effective at protecting women against persistent HPV 16 and 18 infection in the anus as it is at protecting them from these infections in the cervix.
Overall, about 30 percent of cervical cancers will not be prevented by these vaccines.
Also, in the case of Gardasil, 10 percent of genital warts will not be prevented by the vaccine. Neither vaccine prevents other sexually transmitted diseases, nor do they treat existing HPV infection or cervical cancer.
In addition, the vaccines can reduce the need for medical care, biopsies, and invasive procedures associated with the follow-up from abnormal Pap tests, thus helping to reduce health care costs and anxieties related to abnormal Pap tests and follow-up procedures.
Diane Harpera researcher for the HPV vaccines, has questioned weather the benefits of the vaccine outweigh its risks in countries where Pap smear screening is common.
Extensive clinical trial and post-marketing safety surveillance data indicate that both Gardasil and Cervarix are well tolerated and safe. There is no proven causal link between the vaccine and serious adverse effects; VAERS reports include any reported effects whether coincidental or causal.
VAERS receives reports on all potential associations between vaccines and adverse events.
Additionally, there have been rare reports of blood clots forming in the heart, lungs, and legs. However, a higher proportion of syncope fainting was seen with Gardasil than is usually seen with other vaccines. The FDA and CDC have reminded health care providers that, to prevent falls and injuries, all vaccine recipients should remain seated or lying down and be closely observed for 15 minutes after vaccination.
There are some factors that exclude people from receiving HPV vaccines. Patients with a hypersensitivity to yeast should not receive Gardasil since yeast is used in its production. People with moderate or severe acute illnesses.Over million doses of HPV vaccines were distributed in the United States from June through December To date, most of CDC’s HPV vaccine safety monitoring and research has focused on Gardasil because it has accounted for the majority of HPV vaccine doses distributed in the United States.
In , Dr. Peter Aaby, Director of the Bandim Health Project, a demographic surveillance system (in Guinea-Bissau, West Africa), which is affiliated with the Statens Serum Institute, identified non-specific adverse vaccine effects which go beyond the specific protective effects of the targeted regardbouddhiste.com noted that these non-specific effects can be beneficial or harmful.
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Human papilloma virus (HPV) vaccines are vaccines that prevent infection by certain types of human papillomavirus. Available vaccines protect against either two, four, or nine types of HPV. All vaccines protect against at least HPV type 16 and 18 that cause the greatest risk of cervical cancer.
It is estimated that they may prevent 70% of cervical cancer, 80% of anal cancer, 60% of vaginal. HPV Vaccination for Cancer Prevention: Progress, Opportunities, and a Renewed Call to Action (Report) In its report, the President’s Cancer Panel concluded that underuse of HPV vaccines was a serious but correctable threat to progress against cancer.
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